Médicaments biologiques
Médicaments biologiques couvre les équipements de séchage sous vide et de lyophilisation de SINOTHERMO utilisés pour préserver la structure et l'activité des protéines, vaccins et autres matières biologiques sensibles. Le traitement sous vide à basse température évite les dommages thermiques qui dénatureraient ces matières, des essais de formulation à l'échelle pilote jusqu'à la lyophilisation en lots de production.
Sécheur sous vide statique à armoire FZG
Catégories : Séchoir à conduction et sous vide, Sécheur à plateaux sous vide
Vacuum Dryer with Pulse Back-Blow Function:
The Square Static Vacuum Dryer comes with spacious hollow heating tubes, warming materials on trays. It is perfect for operating at low temperatures in a vacuum, suitable for handling explosive and heat-sensitive materials while maintaining their original characteristics and properties.
- Input:
- Liquids, Slurries, Pastes and Thick Materials
- Output:
- Lump Solids with 3%-5% moisture content
- Temperature:
- Heat source temperature <100°C
DW-Sécheur à Bande
Catégories : Séchoir à convection
Continuous Convection Dryer with Mesh Belt:
The Belt Dryer can be configured with single or multiple mesh-belt layers, spreading material evenly for directional hot-air drying. Belt speed adjusts to each material's temperature and moisture content, so it runs at comparatively low temperatures while continuously processing large batches.
- Input:
- Permeable solids in sheets, strips, granules or blocks
- Output:
- Sheet, strip, granule or block solids with 3%–8% moisture content
- Temperature:
- Inlet air temperature < 200°C
- Additional Feature:
- Cooling
Enrobeur-Granulateur en Lit Fluidisé Wurster FLP
Catégories : Granulateur et extrudeur, Granulateur à lit fluidisé
All-in-One Mixing, Granulating, Coating, and Drying:
After the main material forms a fluidized bed at the bottom, granules are created with the aid of adhesive sprayed from the top nozzles in the granulating chamber. Subsequently, coating material is sprayed onto the granules from bottom or side nozzles within the chamber for effective coating.
- Input:
- Main ingredient as powder (for granulation) or granules and pellets (for coating), with adhesive or coating material in liquid form
- Output:
- Solid medium-sized granules with 3%–5% moisture content
- Type:
- Spray Fluidized Bed, Wet Granulation
- Additional Features:
- Mixing, Coating, Drying, Cooling
ZLG-Sécheur à Lit Fluidisé Vibrant Horizontal
Catégories : Séchoir à convection, Sécheur à lit fluidisé, Sécheur vibrant
Continuous Drying Solution for Granular Materials:
Operating on the principle of fluidization combined with vibration, the Vibrating Fluid Bed Dryer processes granules by circulating them on heated air that dries them evenly. This approach minimizes surface damage, prevents pollution thanks to its enclosed design, and gives granules time to settle — facilitating stable, continuous production.
- Input:
- Granules with moisture content < 20%
- Output:
- Granules with 1%–5% moisture content
- Temperature:
- Inlet air temperature < 200°C
- Additional Feature:
- Cooling
Granulateur Extrudeuse à Vis SET
Catégories : Granulateur et extrudeur
Wet Granulation with Screw Extrusion Process:
By utilizing an extrusion process, this wet-granulation machine leverages the self-viscosity of a solid-liquid dispersion to bond powder particles, producing granules of consistent shape and size. The screw-extrusion mechanism generates enough force to form pellets without always requiring a binder — particularly suitable for high-viscosity materials. Optional water cooling is available.
- Input:
- Solid-liquid mixture (predominantly solid)
- Output:
- Moist cylindrical granules
- Type:
- Extrusion Granulation, Wet Granulation
GHL-Granulateur à Mélange Humide Rapide
Catégories : Granulateur et extrudeur
Cutting-Edge Wet Granulation Technology:
A paddle at the base swiftly mixes powders and sticky binders within a cylindrical bowl, while a rapid chopper on the side breaks the mixture into wet granules to prevent clumping. This fast process combines mixing and granule formation within minutes, and the Wet Rapid Mixing Granulator can provide heating or cooling as needed.
- Input:
- Main material in powder form, binding agent as paste
- Output:
- Solid, loose granules with approximately 15% moisture content
- Type:
- Mixing Granulation, Wet Granulation
- Additional Features:
- Mixing, Mild Crushing, Heating, Cooling
Sécheur par Pulvérisation à Circulation Fermée GXP
Catégories : Séchoir à convection, Sécheur par pulvérisation
Optimal Drying for Sensitive Materials:
This explosion-proof spray dryer operates in a sealed environment, using inert gas as the drying medium to fully recover solvents from raw materials. The recyclable drying medium provides superior protection for sensitive materials.
- Input:
- Solutions, Emulsions, Suspensions
- Output:
- Powder with 3%–8% moisture content
- Temperature:
- Inlet air temperature range of 100°C to 300°C
- Suitability:
- Anaerobic, explosion-proof and low-temperature conditions
Sécheur par Pulvérisation ZLPG pour Extraits
Catégories : Séchoir à convection, Sécheur par pulvérisation
Specialized Spray Dryer for Extracts:
The Extract Spray Dryer features a cylinder equipped with a cooling system specifically designed for drying extracts while keeping wall temperatures below 80°C. It includes an airbrush that cleans the walls during operation to prevent adhesion and protect the powder from burning.
- Input:
- Extracts (Liquid)
- Output:
- Extracts (Powder) with 3%–8% moisture content
- Temperature:
- Inlet air temperature range of 140°C to 180°C
- Additional Features:
- Freeze dehumidification, Air brush for tower cleaning
PGL-Granulateur à pulvérisation en lit fluidisé
Catégories : Granulateur et extrudeur, Granulateur à lit fluidisé
Combines Mixing, Granulating and Drying for High-Excipient Granulation:
Excipient-rich granulation finds an ideal match in this unit. Excipients in the hopper form a fluidized bed that acts as seeds or carriers, while the main material — typically a liquid extract making up a smaller proportion of the batch — is sprayed from above and merges at the bed's edge for granulation. This method is particularly suited to heat-sensitive materials.
- Input:
- Carrier materials in powder form, main material in liquid form
- Output:
- Solid medium-sized granules, 3%–5% moisture content
- Type:
- Spray Fluidized Bed, Wet Granulation
- Additional Features:
- Mixing, Drying, Cooling
ZYG-Sécheur Horizontal à Disques sous Vide
Catégories : Séchoir à conduction et sous vide
Vacuum Conduction Dryer with Hollow Disc Stirrers:
The Vacuum Horizontal Disc Dryer has a large-area jacket for heating and hollow disc stirrers that enhance the heating surface. It performs better than rake and paddle vacuum dryers in heating efficiency for many materials, is suited to low-temperature vacuum operation, and is ideal for handling flammable, explosive, organic-solvent-based and heat-sensitive materials.
- Input:
- Liquids, Slurries, Pastes, and Mashes
- Output:
- Powder with 3%–10% moisture content
- Temperature:
- Heat source temperature 50°C to 200°C
- Additional Feature:
- Stirring, Mild Crushing
Lyophilisateur Pilote
Catégories : Lyophilisateur, Lyophilisateur commercial, Lyophilisateur de laboratoire
Cutting-Edge Precision Freeze Drying Technology:
The Pilot Freeze Dryer stands out for its accuracy and precision, making it a crucial tool in sectors like pharmaceuticals, biotechnology and food processing. It upholds the chemical and structural integrity of products by drying them at low temperature under vacuum, and offers configurable shelf layouts to accommodate substances ranging from delicate biological materials to sturdy chemical compounds.
- Input:
- Liquids, extracts, blocks, slices, strips
- Output:
- Dehydrated liquids, concentrated extracts, dried blocks, slices and strips
- Temperature:
- Capable of achieving temperatures as low as -55°C
- Additional Feature:
- Defrost System
Lyophilisateur de paillasse
Catégories : Lyophilisateur, Lyophilisateur de laboratoire
Compact Freeze Drying for Lab and Small-Scale Production:
The Benchtop Freeze Dryer brings full freeze-drying capability to a footprint that fits a lab bench or small production room. Automated controls streamline each cycle, while low-temperature vacuum drying preserves the structure and properties of pharmaceutical materials, biological specimens and food products — a dependable choice for drug and vaccine preparation, sample preservation and small-batch trials.
- Input:
- Pharmaceutical materials, biological specimens, food products
- Output:
- Freeze-dried product with preserved structure and properties
- Type:
- Laboratory / small-scale vacuum freeze drying
- Cold Trap:
- Down to -80°C
Lyophilisateur Rond
Catégories : Lyophilisateur, Lyophilisateur commercial, Lyophilisateur industriel
Maximize Output with Cylindrical-Chamber Freeze Drying:
The Round Freeze Dryer uses a cylindrical chamber that maximizes space usage for large-batch freeze drying at industrial scale. Built to handle big batches without compromising quality or efficiency, it helps companies expand freeze-drying capacity for pharmaceuticals, biological samples and food products while minimizing waste.
- Input:
- Pharmaceuticals, biological samples, food products (large batches)
- Output:
- Freeze-dried product with extended shelf life
- Temperature:
- Adjustable -50°C to -80°C
- Design:
- Cylindrical high-capacity chamber
Séchage doux pour matières biologiques sensibles
Le sécheur en armoire sous vide statique FZG et les Lyophilisateurs Pilote, De paillasse et Rond préservent la structure et l'activité des protéines, vaccins et autres médicaments biologiques grâce au séchage sous vide à basse température, tandis que les sécheurs par pulvérisation à circulation fermée GXP et à extraits ZLPG traitent les intermédiaires biologiques sensibles aux solvants.
Répondre aux exigences strictes de traitement des médicaments biologiques
La lyophilisation sous vide à basse température est la méthode standard pour préserver la structure des protéines et l'activité biologique. Le séchage par pulvérisation à circulation fermée protège les intermédiaires biologiques sensibles à l'oxygène et aux solvants pendant le traitement. Les équipements à l'échelle pilote soutiennent le développement de formulations avant de s'engager dans la lyophilisation à l'échelle de production.
En savoir plus
Pharmaceuticals →
Le secteur pharmaceutique plus large dans lequel s'inscrit le traitement des médicaments biologiques.
Spices and Flavorings →
Partage les équipements de lyophilisation pour les extraits naturels sensibles.
Chemicals →
Partage les équipements de séchage sous vide pour les intermédiaires chimiques sensibles.
