Farmaceutica

Le apparecchiature per essiccazione, granulazione e miscelazione SINOTHERMO servono l'industria farmaceutica con un controllo preciso della temperatura, lavorazione a tenuta stagna e design orientato al GMP, proteggendo i principi attivi dalla degradazione termica.

Essiccatore CD

Categorie: Essiccatore a conduzione e sottovuoto

Continuous Drying for Liquid and Paste-like Materials:

The CD Dryer is designed for continuous drying of liquids and pastes. Utilizing indirectly heated discs, the dryer efficiently transfers heat to the material, creating a thin layer for rapid evaporation. This method ensures effective drying and consistent product quality.

Input:: Liquid and Pasty Materials
Output:: Dried Solids (flake or powder, depending on application)
Heat Transfer Coefficient:: Overall heat transfer coefficient: 2,300W/m²k
Thermal Efficiency:: 80 to 85% thermal efficiency

Essiccatore Spray Centrifugo LPG

Categorie: Essiccatore a convezione, Essiccatore Spray

Advanced Liquid-to-Powder Process:

A high-speed centrifugal atomizer at the tower's peak transforms materials into super fine liquid drops that dry quickly upon contact with hot air — perfect for precise particle size, moisture, density and shape standards.

Input:: Solutions, Emulsions, Suspensions
Output:: Powder with 3%-5% moisture content
Temperature:: Inlet air temperature range of 150°C to 500°C

Essiccatore a Vassoi CTC-Tray

Categorie: Essiccatore a convezione

Hot Air Circulation Batch Drying:

The Hot Air Circulation Tray Dryer warms materials evenly on trays with forced hot-air circulation. Simple, reliable batch drying for granules, powders, herbs and food ingredients.

Input:: Granules, Powders, Herbs, Sliced Materials
Output:: Dried solids with uniform moisture content
Temperature:: Hot air temperature ≤140°C

ZPG-Essiccatore a Rastrello a Vuoto

Categorie: Essiccatore a conduzione e sottovuoto

Rake Agitator Vacuum Conduction Dryer:

The Rake Dryer comes with a large-area jacket heating system and a rake agitator that increases the heating surface area, making it easier to move and heat materials. Operating under vacuum, it is perfect for handling flammable, organic solvent-based and heat-sensitive materials.

Input:: Pastes, Slurries, Viscous Materials
Output:: Powder with 3%-8% moisture content
Temperature:: Heat source temperature <150°C

FZG-Essiccatore Statico a Vuoto a Vassoi

Categorie: Essiccatore a conduzione e sottovuoto, Essiccatore a Vassoi a Vuoto

Vacuum Dryer with Pulse Back-Blow Function:

The Square Static Vacuum Dryer comes with spacious hollow heating tubes, warming materials on trays. It is perfect for operating at low temperatures in a vacuum, suitable for handling explosive and heat-sensitive materials while maintaining their original characteristics and properties.

Input:: Liquids, Slurries, Pastes and Thick Materials
Output:: Lump Solids with 3%-5% moisture content
Temperature:: Heat source temperature <100°C

SZG-Essiccatore Rotante a Doppio Cono sotto Vuoto

Categorie: Essiccatore a conduzione e sottovuoto

Dependable Vacuum Conduction Drying Solution:

The Double Cone Rotary Vacuum Dryer includes a heating system and an interior free of dead angles, making it highly adaptable. With its barrel rotation it effectively blends the contents — suitable for low-temperature vacuum operation with organic solvent-based and heat-sensitive materials.

Input:: Powders, Granules
Output:: Powder with 3%-5% moisture content
Temperature:: Heat source temperature <150°C
Additional Feature:: Rotating blending

DZLG-Essiccatore Sottovuoto Conico a Nastro

Categorie: Essiccatore a conduzione e sottovuoto

Conical Vacuum Dryer with Hollow Ribbon Technology:

With its jacket and ribbon design, the Conical Vacuum Dryer provides a large heating surface, efficient material loading and smooth discharge without any dead angles. The ribbon facilitates mixing for heating and blending — perfect for low-temperature vacuum conditions with explosive and heat-sensitive materials.

Input:: Loose powdery, granular solids
Output:: Powder with 3%-5% moisture content
Temperature:: Heat source temperature <200°C
Additional Feature:: Stirring and mixing

DW-Essiccatore a nastro

Categorie: Essiccatore a convezione

Continuous Convection Dryer with Mesh Belt:

The Belt Dryer can be configured with single or multiple mesh-belt layers, spreading material evenly for directional hot-air drying. Belt speed adjusts to each material's temperature and moisture content, so it runs at comparatively low temperatures while continuously processing large batches.

Input:: Permeable solids in sheets, strips, granules or blocks
Output:: Sheet, strip, granule or block solids with 3%–8% moisture content
Temperature:: Inlet air temperature < 200°C
Additional Feature:: Cooling

Ricopritrice a Granulazione a Letto Fluido Wurster FLP

Categorie: Granulatore ed estrusore, Granulatore a Letto Fluido

All-in-One Mixing, Granulating, Coating, and Drying:

After the main material forms a fluidized bed at the bottom, granules are created with the aid of adhesive sprayed from the top nozzles in the granulating chamber. Subsequently, coating material is sprayed onto the granules from bottom or side nozzles within the chamber for effective coating.

Input:: Main ingredient as powder (for granulation) or granules and pellets (for coating), with adhesive or coating material in liquid form
Output:: Solid medium-sized granules with 3%–5% moisture content
Type:: Spray Fluidized Bed, Wet Granulation
Additional Features:: Mixing, Coating, Drying, Cooling

ZLG - Essiccatore a Letto Fluido Vibrante Orizzontale

Categorie: Essiccatore a convezione, Essiccatore a Letto Fluidizzato, Essiccatore Vibrante

Continuous Drying Solution for Granular Materials:

Operating on the principle of fluidization combined with vibration, the Vibrating Fluid Bed Dryer processes granules by circulating them on heated air that dries them evenly. This approach minimizes surface damage, prevents pollution thanks to its enclosed design, and gives granules time to settle — facilitating stable, continuous production.

Input:: Granules with moisture content < 20%
Output:: Granules with 1%–5% moisture content
Temperature:: Inlet air temperature < 200°C
Additional Feature:: Cooling

Granulatore a Estrusore a Vite SET

Categorie: Granulatore ed estrusore

Wet Granulation with Screw Extrusion Process:

By utilizing an extrusion process, this wet-granulation machine leverages the self-viscosity of a solid-liquid dispersion to bond powder particles, producing granules of consistent shape and size. The screw-extrusion mechanism generates enough force to form pellets without always requiring a binder — particularly suitable for high-viscosity materials. Optional water cooling is available.

Input:: Solid-liquid mixture (predominantly solid)
Output:: Moist cylindrical granules
Type:: Extrusion Granulation, Wet Granulation

GHL-Granulatore a Miscelazione Umida Rapida

Categorie: Granulatore ed estrusore

Cutting-Edge Wet Granulation Technology:

A paddle at the base swiftly mixes powders and sticky binders within a cylindrical bowl, while a rapid chopper on the side breaks the mixture into wet granules to prevent clumping. This fast process combines mixing and granule formation within minutes, and the Wet Rapid Mixing Granulator can provide heating or cooling as needed.

Input:: Main material in powder form, binding agent as paste
Output:: Solid, loose granules with approximately 15% moisture content
Type:: Mixing Granulation, Wet Granulation
Additional Features:: Mixing, Mild Crushing, Heating, Cooling

Miscelatore Rotante a Tamburo

Categorie: Miscelatore, Miscelatore Rotante

Innovative Multi-Axis Motion Rotary Drum Mixer:

The Rotary Drum Mixer transforms the mixing process by moving and combining motions on the x, y and z axes. This method guarantees thorough mixing of powders and granules with simplicity and effectiveness, making it an ideal choice for dry-mixing applications.

Input:: Solid powders, Granules
Type:: Dry Mixing

Mulino a martelli

Categorie: Polverizzatore

Versatile Pulverizing Technology:

With its versatile pulverizing technology, the Hammer Mill finds applications across industries. Its adaptable design features customizable blades, collection systems, cooling mechanisms and dust-removal systems, making it suitable for processing a wide range of materials.

Input:: Brittle solids (< 15mm)
Output:: 50 to 150 mesh

WFJ-Polverizzatore a Impatto

Categorie: Polverizzatore

Optimal Choice for Ultra-Fine Granularity:

The Impact Pulverizer grinds materials to a particle size of 400 mesh or even finer, streamlining manufacturing processes. It can additionally be equipped with a cyclone collector and bag-type dust remover for cleaner processing.

Input:: Brittle Solids (up to 10mm)
Output:: 80 to 450 mesh

Essiccatore Spray a Circolazione Chiusa GXP

Categorie: Essiccatore a convezione, Essiccatore Spray

Optimal Drying for Sensitive Materials:

This explosion-proof spray dryer operates in a sealed environment, using inert gas as the drying medium to fully recover solvents from raw materials. The recyclable drying medium provides superior protection for sensitive materials.

Input:: Solutions, Emulsions, Suspensions
Output:: Powder with 3%–8% moisture content
Temperature:: Inlet air temperature range of 100°C to 300°C
Suitability:: Anaerobic, explosion-proof and low-temperature conditions

ZLPG-Essiccatore Spray per Estratti

Categorie: Essiccatore a convezione, Essiccatore Spray

Specialized Spray Dryer for Extracts:

The Extract Spray Dryer features a cylinder equipped with a cooling system specifically designed for drying extracts while keeping wall temperatures below 80°C. It includes an airbrush that cleans the walls during operation to prevent adhesion and protect the powder from burning.

Input:: Extracts (Liquid)
Output:: Extracts (Powder) with 3%–8% moisture content
Temperature:: Inlet air temperature range of 140°C to 180°C
Additional Features:: Freeze dehumidification, Air brush for tower cleaning

FG-Essiccatore a Letto Fluidizzato Verticale

Categorie: Essiccatore a convezione, Essiccatore a Letto Fluidizzato

Solution for Batch Drying of Granules and Powder:

The Vertical Fluid Bed Dryer fluidizes materials with an upward air stream that promotes contact for quick drying or cooling. Designed specifically for batch production, it allows taller bed heights than horizontal fluidized bed dryers and is commonly paired with wet granulation machines.

Input:: Powders and Granules, moisture < 20%
Output:: Powders and Granules, moisture 3%–5%
Temperature:: Inlet air temperature < 100°C
Additional Feature:: Convertible to a spray fluidized bed granulator

XF-Essiccatore a Letto Fluido Orizzontale

Categorie: Essiccatore a convezione, Essiccatore a Letto Fluidizzato

Versatile Continuous Drying for Granules and Powder:

The Horizontal Fluidized Bed Dryer aerates damp materials with an upward air stream to dry or cool them. Built for continuous manufacturing, it offers residence times from a few seconds to minutes, ensuring effective processing.

Input:: Powders and Granules, moisture < 20%
Output:: Powders and Granules, moisture 3%–5%
Temperature:: Inlet air temperature < 100°C
Additional Feature:: Cooling

GFG-Essiccatore a Letto Fluidizzato Verticale con Miscelazione

Categorie: Essiccatore a convezione, Essiccatore a Letto Fluidizzato

Fluidized Bed Drying with Built-In Mixing:

The Vertical Blending Fluidized Bed Dryer is equipped with a mixing mechanism that helps form a fluidized bed inside the vessel when handling heavy loads. Ideal for mass production, it can process thick materials and is typically paired with wet granulation setups.

Input:: Powder and Granules, moisture < 20%
Output:: Powder and Granules, moisture 3%–5%
Temperature:: Inlet air temperature < 100°C
Additional Feature:: Stirring, Cooling

FL-Granulatore a Letto Fluidizzato

Categorie: Granulatore ed estrusore, Granulatore a Letto Fluido

All-in-One Mixing, Granulating, and Drying:

Materials form a fluidized bed at the bottom, where granules are created in the granulation chamber with the help of spray nozzles dispensing binder. The hopper allows several raw materials to be added and mixed during the fluidization process.

Input:: Main ingredient as powder, adhesive in liquid form
Output:: Solid medium-sized granules with 3%–5% moisture content
Type:: Spray Fluidized Bed, Wet Granulation
Additional Features:: Mixing, Drying, Cooling

PGL-Granulatore Spray a Letto Fluidizzato

Categorie: Granulatore ed estrusore, Granulatore a Letto Fluido

Combines Mixing, Granulating and Drying for High-Excipient Granulation:

Excipient-rich granulation finds an ideal match in this unit. Excipients in the hopper form a fluidized bed that acts as seeds or carriers, while the main material — typically a liquid extract making up a smaller proportion of the batch — is sprayed from above and merges at the bed's edge for granulation. This method is particularly suited to heat-sensitive materials.

Input:: Carrier materials in powder form, main material in liquid form
Output:: Solid medium-sized granules, 3%–5% moisture content
Type:: Spray Fluidized Bed, Wet Granulation
Additional Features:: Mixing, Drying, Cooling

Miscelatore a V

Categorie: Miscelatore, Miscelatore Rotante

Multifunctional and Efficient Blender:

The V Blender's unique V-shaped chamber and rotation use gravity to gently mix materials, ensuring even distribution without damage.

Input:: Solid powders, Granules
Type:: Dry Mixing

Miscelatore a Doppio Cono

Categorie: Miscelatore, Miscelatore Conico, Miscelatore Rotante

Mixer with Multiple Motion Options:

Available in single-cone or double-cone designs, the Double Cone Blender features a sealed chamber that rocks back and forth along the X axis in repeated cycles to mix materials, ensuring high-quality results.

Input:: Solid Powders, Granules
Type:: Dry Mixing

Miscelatore CH-Sigma

Categorie: Miscelatore, Miscelatore Orizzontale

Straightforward Design, Eliminating Awkward Corners:

The Sigma Mixer comes with a trough-shaped mixing chamber and sigma-shaped paddles mounted on the shaft, providing both sealing and mixing capabilities. Perfect for blending powders, granules and small amounts of liquid.

Input:: Powders, Granules, Small Amounts of Liquid
Type:: Dry Mixing, Mild Wet Mixing

WLDH-Miscelatore a Nastro Orizzontale

Categorie: Miscelatore, Miscelatore Orizzontale, Miscelatore a Nastro

Equipped with Horizontal Screw Belts:

The Horizontal Ribbon Mixer offers efficient material blending. Its cylinder holds a shaft with surrounding ribbon belts that rotate at equal speed: the outer belts move material from both ends toward the center while the inner belts move it from the center back out, folding the batch together for thorough mixing.

Input:: Powders, Granules, Small amounts of liquid
Type:: Dry Mixing, Mild Wet Mixing

Miscelatore a Coclea con Nastro Conico DLH

Categorie: Miscelatore, Miscelatore Conico, Miscelatore a Nastro, Miscelatore a Coclea

Equipped with Rotating Spiral Belt:

A screw encased in a ribbon rotates simultaneously to create a swirling motion, lifting material upward in a spiral from the base of the cone before it descends by gravity. Optional features such as spray atomization and jacket heating or cooling are also available.

Input:: Solids, Powders, Granules, Liquids
Type:: Dry Mixing, Wet Mixing
Additional Features:: Humidifying, Drying, Cooling

YK-Granulatore Oscillante

Categorie: Granulatore ed estrusore

Efficient, Versatile Oscillating Granulator:

The Oscillating Granulator uses a special back-and-forth motion to softly turn moist powder into even, round granules. Variable oscillation frequency and amplitude allow precise control of particle size and density, in a compact design with simple operation and low maintenance requirements.

Input:: Moist powder mixed with a binder
Output:: Wet cylindrical granules
Type:: Dry Granulation, Wet Granulation
Additional Feature:: Mixing

Granulatore a Cestello ZLB

Categorie: Granulatore ed estrusore

Efficient Wet Extrusion Granulator:

Moist powder is pushed through a mesh by rotating blades during extrusion to form quality granules. The Basket Granulator offers steady granulation rates, visually appealing particles, an automated discharge process and high output levels.

Input:: Moist powder mixed with a binder
Output:: Wet cylindrical granules
Type:: Extrusion Granulation, Wet Granulation
Additional Feature:: Mixing

Granulatore a Compressione a Secco GKDH

Categorie: Granulatore ed estrusore

Additive-Free Dry Granulation Process:

Dry raw materials are compressed under pressure to form solid flakes, which are then processed into granules of the desired size — forming granules through pressure alone, with no liquid binder or added moisture.

Input:: Powder
Output:: Solid Granules
Type:: Dry Granulation
Additional Features:: Crushing, Screening

ZYG-Essiccatore a Disco Orizzontale sotto Vuoto

Categorie: Essiccatore a conduzione e sottovuoto

Vacuum Conduction Dryer with Hollow Disc Stirrers:

The Vacuum Horizontal Disc Dryer has a large-area jacket for heating and hollow disc stirrers that enhance the heating surface. It performs better than rake and paddle vacuum dryers in heating efficiency for many materials, is suited to low-temperature vacuum operation, and is ideal for handling flammable, explosive, organic-solvent-based and heat-sensitive materials.

Input:: Liquids, Slurries, Pastes, and Mashes
Output:: Powder with 3%–10% moisture content
Temperature:: Heat source temperature 50°C to 200°C
Additional Feature:: Stirring, Mild Crushing

Liofilizzatore Pilota

Categorie: Liofilizzatore, Liofilizzatore Commerciale, Liofilizzatore da Laboratorio

Cutting-Edge Precision Freeze Drying Technology:

The Pilot Freeze Dryer stands out for its accuracy and precision, making it a crucial tool in sectors like pharmaceuticals, biotechnology and food processing. It upholds the chemical and structural integrity of products by drying them at low temperature under vacuum, and offers configurable shelf layouts to accommodate substances ranging from delicate biological materials to sturdy chemical compounds.

Input:: Liquids, extracts, blocks, slices, strips
Output:: Dehydrated liquids, concentrated extracts, dried blocks, slices and strips
Temperature:: Capable of achieving temperatures as low as -55°C
Additional Feature:: Defrost System

Liofilizzatore da banco

Categorie: Liofilizzatore, Liofilizzatore da Laboratorio

Compact Freeze Drying for Lab and Small-Scale Production:

The Benchtop Freeze Dryer brings full freeze-drying capability to a footprint that fits a lab bench or small production room. Automated controls streamline each cycle, while low-temperature vacuum drying preserves the structure and properties of pharmaceutical materials, biological specimens and food products — a dependable choice for drug and vaccine preparation, sample preservation and small-batch trials.

Input:: Pharmaceutical materials, biological specimens, food products
Output:: Freeze-dried product with preserved structure and properties
Type:: Laboratory / small-scale vacuum freeze drying
Cold Trap:: Down to -80°C

Liofilizzatore Rotondo

Categorie: Liofilizzatore, Liofilizzatore Commerciale, Liofilizzatore Industriale

Maximize Output with Cylindrical-Chamber Freeze Drying:

The Round Freeze Dryer uses a cylindrical chamber that maximizes space usage for large-batch freeze drying at industrial scale. Built to handle big batches without compromising quality or efficiency, it helps companies expand freeze-drying capacity for pharmaceuticals, biological samples and food products while minimizing waste.

Input:: Pharmaceuticals, biological samples, food products (large batches)
Output:: Freeze-dried product with extended shelf life
Temperature:: Adjustable -50°C to -80°C
Design:: Cylindrical high-capacity chamber

Liofilizzatore ad Armadio

Categorie: Liofilizzatore, Liofilizzatore Industriale

State-of-the-Art Cabinet Freeze Dryer for Industrial Use:

This Cabinet Freeze Dryer is crafted to extract moisture efficiently from a wide array of products. Using a freeze-drying technique, it lowers temperatures to optimal levels and converts moisture directly from solid to vapor — ensuring top-notch preservation and quality without a liquid phase.

Input:: Pharmaceutical ingredients, food products, chemical compounds
Output:: Stably dried and preserved materials
Temperature:: -50°C to -80°C

Apparecchiature per compresse, polveri e lavorazione sterile

Essiccatori sotto vuoto e ad armadio statico trattano API e intermedi termosensibili; ricopritrici Wurster e granulatori a letto fluido costruiscono e ricoprono i granuli per compresse; miscelatori sigma e a nastro miscelano eccipienti e principi attivi; i liofilizzatori liofilizzano prodotti biologici e iniettabili dalla scala pilota a quella produttiva.

Perché i produttori farmaceutici scelgono questa gamma

L'essiccazione delicata sotto vuoto e per conduzione preserva la potenza del principio attivo senza degradazione termica. Il rivestimento Wurster consente formulazioni per mascherare il sapore e a rilascio controllato. I liofilizzatori coprono l'intero percorso, dalle prove da banco in R&S alla liofilizzazione di interi lotti di produzione. La costruzione resistente alla corrosione e facile da pulire soddisfa i requisiti igienici farmaceutici.

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