Granulatore ed estrusore
Apparecchiature di granulazione a umido, a secco e a letto fluido per la produzione di granuli uniformi e a scorrimento libero destinati a compresse, polveri istantanee e particelle ingegnerizzate.
Ricopritrice a Granulazione a Letto Fluido Wurster FLP
Categorie: Granulatore ed estrusore, Granulatore a Letto Fluido
All-in-One Mixing, Granulating, Coating, and Drying:
After the main material forms a fluidized bed at the bottom, granules are created with the aid of adhesive sprayed from the top nozzles in the granulating chamber. Subsequently, coating material is sprayed onto the granules from bottom or side nozzles within the chamber for effective coating.
- Input:
- Main ingredient as powder (for granulation) or granules and pellets (for coating), with adhesive or coating material in liquid form
- Output:
- Solid medium-sized granules with 3%–5% moisture content
- Type:
- Spray Fluidized Bed, Wet Granulation
- Additional Features:
- Mixing, Coating, Drying, Cooling
Granulatore a Estrusore a Vite SET
Categorie: Granulatore ed estrusore
Wet Granulation with Screw Extrusion Process:
By utilizing an extrusion process, this wet-granulation machine leverages the self-viscosity of a solid-liquid dispersion to bond powder particles, producing granules of consistent shape and size. The screw-extrusion mechanism generates enough force to form pellets without always requiring a binder — particularly suitable for high-viscosity materials. Optional water cooling is available.
- Input:
- Solid-liquid mixture (predominantly solid)
- Output:
- Moist cylindrical granules
- Type:
- Extrusion Granulation, Wet Granulation
GHL-Granulatore a Miscelazione Umida Rapida
Categorie: Granulatore ed estrusore
Cutting-Edge Wet Granulation Technology:
A paddle at the base swiftly mixes powders and sticky binders within a cylindrical bowl, while a rapid chopper on the side breaks the mixture into wet granules to prevent clumping. This fast process combines mixing and granule formation within minutes, and the Wet Rapid Mixing Granulator can provide heating or cooling as needed.
- Input:
- Main material in powder form, binding agent as paste
- Output:
- Solid, loose granules with approximately 15% moisture content
- Type:
- Mixing Granulation, Wet Granulation
- Additional Features:
- Mixing, Mild Crushing, Heating, Cooling
FL-Granulatore a Letto Fluidizzato
Categorie: Granulatore ed estrusore, Granulatore a Letto Fluido
All-in-One Mixing, Granulating, and Drying:
Materials form a fluidized bed at the bottom, where granules are created in the granulation chamber with the help of spray nozzles dispensing binder. The hopper allows several raw materials to be added and mixed during the fluidization process.
- Input:
- Main ingredient as powder, adhesive in liquid form
- Output:
- Solid medium-sized granules with 3%–5% moisture content
- Type:
- Spray Fluidized Bed, Wet Granulation
- Additional Features:
- Mixing, Drying, Cooling
PGL-Granulatore Spray a Letto Fluidizzato
Categorie: Granulatore ed estrusore, Granulatore a Letto Fluido
Combines Mixing, Granulating and Drying for High-Excipient Granulation:
Excipient-rich granulation finds an ideal match in this unit. Excipients in the hopper form a fluidized bed that acts as seeds or carriers, while the main material — typically a liquid extract making up a smaller proportion of the batch — is sprayed from above and merges at the bed's edge for granulation. This method is particularly suited to heat-sensitive materials.
- Input:
- Carrier materials in powder form, main material in liquid form
- Output:
- Solid medium-sized granules, 3%–5% moisture content
- Type:
- Spray Fluidized Bed, Wet Granulation
- Additional Features:
- Mixing, Drying, Cooling
YK-Granulatore Oscillante
Categorie: Granulatore ed estrusore
Efficient, Versatile Oscillating Granulator:
The Oscillating Granulator uses a special back-and-forth motion to softly turn moist powder into even, round granules. Variable oscillation frequency and amplitude allow precise control of particle size and density, in a compact design with simple operation and low maintenance requirements.
- Input:
- Moist powder mixed with a binder
- Output:
- Wet cylindrical granules
- Type:
- Dry Granulation, Wet Granulation
- Additional Feature:
- Mixing
Granulatore a Cestello ZLB
Categorie: Granulatore ed estrusore
Efficient Wet Extrusion Granulator:
Moist powder is pushed through a mesh by rotating blades during extrusion to form quality granules. The Basket Granulator offers steady granulation rates, visually appealing particles, an automated discharge process and high output levels.
- Input:
- Moist powder mixed with a binder
- Output:
- Wet cylindrical granules
- Type:
- Extrusion Granulation, Wet Granulation
- Additional Feature:
- Mixing
Granulatore a Compressione a Secco GKDH
Categorie: Granulatore ed estrusore
Additive-Free Dry Granulation Process:
Dry raw materials are compressed under pressure to form solid flakes, which are then processed into granules of the desired size — forming granules through pressure alone, with no liquid binder or added moisture.
- Input:
- Powder
- Output:
- Solid Granules
- Type:
- Dry Granulation
- Additional Features:
- Crushing, Screening
Granulazione a Umido, a Secco e a Letto Fluido in un'Unica Gamma
La gamma di granulatori SINOTHERMO comprende il rivestimento a letto fluidizzato Wurster, l'estrusione a coclea, la miscelazione umida rapida, la granulazione a letto fluido e la granulazione per nebulizzazione per i processi a umido, oltre a granulatori oscillanti, a cestello e a compressione a secco per i processi a secco, coprendo compresse, polveri istantanee e particelle ingegnerizzate.
Percorso di Granulazione a Umido vs. a Secco
La granulazione a umido lega le polveri con un liquido: la miscelazione rapida (GHL) forma la massa umida, quindi l'estrusione (SET) o la nebulizzazione a letto fluido (FL, PGL) modella ed essicca i granuli in un unico passaggio; il rivestimento Wurster (FLP) stratifica i rivestimenti sulle particelle. La granulazione a secco compatta le polveri senza aggiunta di liquidi: i granulatori oscillanti (YK) e a cestello (ZLB) frantumano i panetti secchi in granuli, mentre la compressione a secco (GKDH) compatta a rulli le polveri fini direttamente in granuli, una soluzione adatta a formulazioni sensibili all'umidità.
Scopri di più
Fluid Bed Granulator →
Uno sguardo più approfondito alle configurazioni di granulazione a umido a letto fluido.
Mixer →
La premiscelazione delle polveri prima della granulazione è una fase a monte comune.
Pharmaceuticals →
La granulazione è un'operazione unitaria fondamentale nella produzione di compresse e polveri farmaceutiche.
