Produtos farmacêuticos
Os equipamentos de secagem, granulação e mistura da SINOTHERMO atendem à fabricação farmacêutica com controle preciso de temperatura, processamento vedado e design orientado às Boas Práticas de Fabricação (BPF) — protegendo os princípios ativos da degradação térmica.
Secador CD
Categorias: Secador de condução e vácuo
Continuous Drying for Liquid and Paste-like Materials:
The CD Dryer is designed for continuous drying of liquids and pastes. Utilizing indirectly heated discs, the dryer efficiently transfers heat to the material, creating a thin layer for rapid evaporation. This method ensures effective drying and consistent product quality.
- Input:
- Liquid and Pasty Materials
- Output:
- Dried Solids (flake or powder, depending on application)
- Heat Transfer Coefficient:
- Overall heat transfer coefficient: 2,300W/m²k
- Thermal Efficiency:
- 80 to 85% thermal efficiency
Secador por Atomização Centrífuga LPG
Categorias: Secador de convecção, Secador por Atomização
Advanced Liquid-to-Powder Process:
A high-speed centrifugal atomizer at the tower's peak transforms materials into super fine liquid drops that dry quickly upon contact with hot air — perfect for precise particle size, moisture, density and shape standards.
- Input:
- Solutions, Emulsions, Suspensions
- Output:
- Powder with 3%-5% moisture content
- Temperature:
- Inlet air temperature range of 150°C to 500°C
Secador de Bandejas CTC
Categorias: Secador de convecção
Hot Air Circulation Batch Drying:
The Hot Air Circulation Tray Dryer warms materials evenly on trays with forced hot-air circulation. Simple, reliable batch drying for granules, powders, herbs and food ingredients.
- Input:
- Granules, Powders, Herbs, Sliced Materials
- Output:
- Dried solids with uniform moisture content
- Temperature:
- Hot air temperature ≤140°C
ZPG-Secador de Raspador a Vácuo
Categorias: Secador de condução e vácuo
Rake Agitator Vacuum Conduction Dryer:
The Rake Dryer comes with a large-area jacket heating system and a rake agitator that increases the heating surface area, making it easier to move and heat materials. Operating under vacuum, it is perfect for handling flammable, organic solvent-based and heat-sensitive materials.
- Input:
- Pastes, Slurries, Viscous Materials
- Output:
- Powder with 3%-8% moisture content
- Temperature:
- Heat source temperature <150°C
FZG-Secador de Câmara a Vácuo Estático
Categorias: Secador de condução e vácuo, Secador de Bandejas a Vácuo
Vacuum Dryer with Pulse Back-Blow Function:
The Square Static Vacuum Dryer comes with spacious hollow heating tubes, warming materials on trays. It is perfect for operating at low temperatures in a vacuum, suitable for handling explosive and heat-sensitive materials while maintaining their original characteristics and properties.
- Input:
- Liquids, Slurries, Pastes and Thick Materials
- Output:
- Lump Solids with 3%-5% moisture content
- Temperature:
- Heat source temperature <100°C
SZG-Secador Rotativo a Vácuo de Cone Duplo
Categorias: Secador de condução e vácuo
Dependable Vacuum Conduction Drying Solution:
The Double Cone Rotary Vacuum Dryer includes a heating system and an interior free of dead angles, making it highly adaptable. With its barrel rotation it effectively blends the contents — suitable for low-temperature vacuum operation with organic solvent-based and heat-sensitive materials.
- Input:
- Powders, Granules
- Output:
- Powder with 3%-5% moisture content
- Temperature:
- Heat source temperature <150°C
- Additional Feature:
- Rotating blending
DZLG-Secador a Vácuo Cônico de Fita
Categorias: Secador de condução e vácuo
Conical Vacuum Dryer with Hollow Ribbon Technology:
With its jacket and ribbon design, the Conical Vacuum Dryer provides a large heating surface, efficient material loading and smooth discharge without any dead angles. The ribbon facilitates mixing for heating and blending — perfect for low-temperature vacuum conditions with explosive and heat-sensitive materials.
- Input:
- Loose powdery, granular solids
- Output:
- Powder with 3%-5% moisture content
- Temperature:
- Heat source temperature <200°C
- Additional Feature:
- Stirring and mixing
DW-Secador de Esteira
Categorias: Secador de convecção
Continuous Convection Dryer with Mesh Belt:
The Belt Dryer can be configured with single or multiple mesh-belt layers, spreading material evenly for directional hot-air drying. Belt speed adjusts to each material's temperature and moisture content, so it runs at comparatively low temperatures while continuously processing large batches.
- Input:
- Permeable solids in sheets, strips, granules or blocks
- Output:
- Sheet, strip, granule or block solids with 3%–8% moisture content
- Temperature:
- Inlet air temperature < 200°C
- Additional Feature:
- Cooling
Revestidora Granuladora de Leito Fluidizado FLP-Wurster
Categorias: Granulador e extrusora, Granulador de Leito Fluidizado
All-in-One Mixing, Granulating, Coating, and Drying:
After the main material forms a fluidized bed at the bottom, granules are created with the aid of adhesive sprayed from the top nozzles in the granulating chamber. Subsequently, coating material is sprayed onto the granules from bottom or side nozzles within the chamber for effective coating.
- Input:
- Main ingredient as powder (for granulation) or granules and pellets (for coating), with adhesive or coating material in liquid form
- Output:
- Solid medium-sized granules with 3%–5% moisture content
- Type:
- Spray Fluidized Bed, Wet Granulation
- Additional Features:
- Mixing, Coating, Drying, Cooling
ZLG-Secador de Leito Fluidizado Vibratório Horizontal
Categorias: Secador de convecção, Secador de Leito Fluidizado, Secador Vibratório
Continuous Drying Solution for Granular Materials:
Operating on the principle of fluidization combined with vibration, the Vibrating Fluid Bed Dryer processes granules by circulating them on heated air that dries them evenly. This approach minimizes surface damage, prevents pollution thanks to its enclosed design, and gives granules time to settle — facilitating stable, continuous production.
- Input:
- Granules with moisture content < 20%
- Output:
- Granules with 1%–5% moisture content
- Temperature:
- Inlet air temperature < 200°C
- Additional Feature:
- Cooling
Granulador Extrusor de Rosca SET
Categorias: Granulador e extrusora
Wet Granulation with Screw Extrusion Process:
By utilizing an extrusion process, this wet-granulation machine leverages the self-viscosity of a solid-liquid dispersion to bond powder particles, producing granules of consistent shape and size. The screw-extrusion mechanism generates enough force to form pellets without always requiring a binder — particularly suitable for high-viscosity materials. Optional water cooling is available.
- Input:
- Solid-liquid mixture (predominantly solid)
- Output:
- Moist cylindrical granules
- Type:
- Extrusion Granulation, Wet Granulation
GHL-Granulador de Mistura Úmida Rápida
Categorias: Granulador e extrusora
Cutting-Edge Wet Granulation Technology:
A paddle at the base swiftly mixes powders and sticky binders within a cylindrical bowl, while a rapid chopper on the side breaks the mixture into wet granules to prevent clumping. This fast process combines mixing and granule formation within minutes, and the Wet Rapid Mixing Granulator can provide heating or cooling as needed.
- Input:
- Main material in powder form, binding agent as paste
- Output:
- Solid, loose granules with approximately 15% moisture content
- Type:
- Mixing Granulation, Wet Granulation
- Additional Features:
- Mixing, Mild Crushing, Heating, Cooling
Misturador de Tambor Rotativo
Categorias: Misturador, Misturador Rotativo
Innovative Multi-Axis Motion Rotary Drum Mixer:
The Rotary Drum Mixer transforms the mixing process by moving and combining motions on the x, y and z axes. This method guarantees thorough mixing of powders and granules with simplicity and effectiveness, making it an ideal choice for dry-mixing applications.
- Input:
- Solid powders, Granules
- Type:
- Dry Mixing
Moinho de Martelo
Categorias: Pulverizador
Versatile Pulverizing Technology:
With its versatile pulverizing technology, the Hammer Mill finds applications across industries. Its adaptable design features customizable blades, collection systems, cooling mechanisms and dust-removal systems, making it suitable for processing a wide range of materials.
- Input:
- Brittle solids (< 15mm)
- Output:
- 50 to 150 mesh
WFJ-Pulverizador de Impacto
Categorias: Pulverizador
Optimal Choice for Ultra-Fine Granularity:
The Impact Pulverizer grinds materials to a particle size of 400 mesh or even finer, streamlining manufacturing processes. It can additionally be equipped with a cyclone collector and bag-type dust remover for cleaner processing.
- Input:
- Brittle Solids (up to 10mm)
- Output:
- 80 to 450 mesh
GXP-Secador por Atomização de Circulação Fechada
Categorias: Secador de convecção, Secador por Atomização
Optimal Drying for Sensitive Materials:
This explosion-proof spray dryer operates in a sealed environment, using inert gas as the drying medium to fully recover solvents from raw materials. The recyclable drying medium provides superior protection for sensitive materials.
- Input:
- Solutions, Emulsions, Suspensions
- Output:
- Powder with 3%–8% moisture content
- Temperature:
- Inlet air temperature range of 100°C to 300°C
- Suitability:
- Anaerobic, explosion-proof and low-temperature conditions
ZLPG-Extract Spray Dryer
Categorias: Secador de convecção, Secador por Atomização
Specialized Spray Dryer for Extracts:
The Extract Spray Dryer features a cylinder equipped with a cooling system specifically designed for drying extracts while keeping wall temperatures below 80°C. It includes an airbrush that cleans the walls during operation to prevent adhesion and protect the powder from burning.
- Input:
- Extracts (Liquid)
- Output:
- Extracts (Powder) with 3%–8% moisture content
- Temperature:
- Inlet air temperature range of 140°C to 180°C
- Additional Features:
- Freeze dehumidification, Air brush for tower cleaning
FG-Secador de Leito Fluidizado Vertical
Categorias: Secador de convecção, Secador de Leito Fluidizado
Solution for Batch Drying of Granules and Powder:
The Vertical Fluid Bed Dryer fluidizes materials with an upward air stream that promotes contact for quick drying or cooling. Designed specifically for batch production, it allows taller bed heights than horizontal fluidized bed dryers and is commonly paired with wet granulation machines.
- Input:
- Powders and Granules, moisture < 20%
- Output:
- Powders and Granules, moisture 3%–5%
- Temperature:
- Inlet air temperature < 100°C
- Additional Feature:
- Convertible to a spray fluidized bed granulator
XF-Secador de Leito Fluidizado Horizontal
Categorias: Secador de convecção, Secador de Leito Fluidizado
Versatile Continuous Drying for Granules and Powder:
The Horizontal Fluidized Bed Dryer aerates damp materials with an upward air stream to dry or cool them. Built for continuous manufacturing, it offers residence times from a few seconds to minutes, ensuring effective processing.
- Input:
- Powders and Granules, moisture < 20%
- Output:
- Powders and Granules, moisture 3%–5%
- Temperature:
- Inlet air temperature < 100°C
- Additional Feature:
- Cooling
GFG-Secador de Leito Fluidizado com Mistura Vertical
Categorias: Secador de convecção, Secador de Leito Fluidizado
Fluidized Bed Drying with Built-In Mixing:
The Vertical Blending Fluidized Bed Dryer is equipped with a mixing mechanism that helps form a fluidized bed inside the vessel when handling heavy loads. Ideal for mass production, it can process thick materials and is typically paired with wet granulation setups.
- Input:
- Powder and Granules, moisture < 20%
- Output:
- Powder and Granules, moisture 3%–5%
- Temperature:
- Inlet air temperature < 100°C
- Additional Feature:
- Stirring, Cooling
FL-Granulador de Leito Fluidizado
Categorias: Granulador e extrusora, Granulador de Leito Fluidizado
All-in-One Mixing, Granulating, and Drying:
Materials form a fluidized bed at the bottom, where granules are created in the granulation chamber with the help of spray nozzles dispensing binder. The hopper allows several raw materials to be added and mixed during the fluidization process.
- Input:
- Main ingredient as powder, adhesive in liquid form
- Output:
- Solid medium-sized granules with 3%–5% moisture content
- Type:
- Spray Fluidized Bed, Wet Granulation
- Additional Features:
- Mixing, Drying, Cooling
PGL-Granulador por Aspersão em Leito Fluidizado
Categorias: Granulador e extrusora, Granulador de Leito Fluidizado
Combines Mixing, Granulating and Drying for High-Excipient Granulation:
Excipient-rich granulation finds an ideal match in this unit. Excipients in the hopper form a fluidized bed that acts as seeds or carriers, while the main material — typically a liquid extract making up a smaller proportion of the batch — is sprayed from above and merges at the bed's edge for granulation. This method is particularly suited to heat-sensitive materials.
- Input:
- Carrier materials in powder form, main material in liquid form
- Output:
- Solid medium-sized granules, 3%–5% moisture content
- Type:
- Spray Fluidized Bed, Wet Granulation
- Additional Features:
- Mixing, Drying, Cooling
Misturador em V
Categorias: Misturador, Misturador Rotativo
Multifunctional and Efficient Blender:
The V Blender's unique V-shaped chamber and rotation use gravity to gently mix materials, ensuring even distribution without damage.
- Input:
- Solid powders, Granules
- Type:
- Dry Mixing
Misturador de Cone Duplo
Categorias: Misturador, Misturador Cônico, Misturador Rotativo
Mixer with Multiple Motion Options:
Available in single-cone or double-cone designs, the Double Cone Blender features a sealed chamber that rocks back and forth along the X axis in repeated cycles to mix materials, ensuring high-quality results.
- Input:
- Solid Powders, Granules
- Type:
- Dry Mixing
Misturador CH-Sigma
Categorias: Misturador, Misturador Horizontal
Straightforward Design, Eliminating Awkward Corners:
The Sigma Mixer comes with a trough-shaped mixing chamber and sigma-shaped paddles mounted on the shaft, providing both sealing and mixing capabilities. Perfect for blending powders, granules and small amounts of liquid.
- Input:
- Powders, Granules, Small Amounts of Liquid
- Type:
- Dry Mixing, Mild Wet Mixing
WLDH-Misturador de Fita Horizontal
Categorias: Misturador, Misturador Horizontal, Misturador de Fita
Equipped with Horizontal Screw Belts:
The Horizontal Ribbon Mixer offers efficient material blending. Its cylinder holds a shaft with surrounding ribbon belts that rotate at equal speed: the outer belts move material from both ends toward the center while the inner belts move it from the center back out, folding the batch together for thorough mixing.
- Input:
- Powders, Granules, Small amounts of liquid
- Type:
- Dry Mixing, Mild Wet Mixing
DLH-Misturador Cônico de Rosca em Fita
Categorias: Misturador, Misturador Cônico, Misturador de Fita, Misturador de Rosca
Equipped with Rotating Spiral Belt:
A screw encased in a ribbon rotates simultaneously to create a swirling motion, lifting material upward in a spiral from the base of the cone before it descends by gravity. Optional features such as spray atomization and jacket heating or cooling are also available.
- Input:
- Solids, Powders, Granules, Liquids
- Type:
- Dry Mixing, Wet Mixing
- Additional Features:
- Humidifying, Drying, Cooling
Granulador Oscilante YK
Categorias: Granulador e extrusora
Efficient, Versatile Oscillating Granulator:
The Oscillating Granulator uses a special back-and-forth motion to softly turn moist powder into even, round granules. Variable oscillation frequency and amplitude allow precise control of particle size and density, in a compact design with simple operation and low maintenance requirements.
- Input:
- Moist powder mixed with a binder
- Output:
- Wet cylindrical granules
- Type:
- Dry Granulation, Wet Granulation
- Additional Feature:
- Mixing
Granulador de Cesto ZLB
Categorias: Granulador e extrusora
Efficient Wet Extrusion Granulator:
Moist powder is pushed through a mesh by rotating blades during extrusion to form quality granules. The Basket Granulator offers steady granulation rates, visually appealing particles, an automated discharge process and high output levels.
- Input:
- Moist powder mixed with a binder
- Output:
- Wet cylindrical granules
- Type:
- Extrusion Granulation, Wet Granulation
- Additional Feature:
- Mixing
Granulador de Compressão a Seco GKDH
Categorias: Granulador e extrusora
Additive-Free Dry Granulation Process:
Dry raw materials are compressed under pressure to form solid flakes, which are then processed into granules of the desired size — forming granules through pressure alone, with no liquid binder or added moisture.
- Input:
- Powder
- Output:
- Solid Granules
- Type:
- Dry Granulation
- Additional Features:
- Crushing, Screening
ZYG-Secador de Disco Horizontal a Vácuo
Categorias: Secador de condução e vácuo
Vacuum Conduction Dryer with Hollow Disc Stirrers:
The Vacuum Horizontal Disc Dryer has a large-area jacket for heating and hollow disc stirrers that enhance the heating surface. It performs better than rake and paddle vacuum dryers in heating efficiency for many materials, is suited to low-temperature vacuum operation, and is ideal for handling flammable, explosive, organic-solvent-based and heat-sensitive materials.
- Input:
- Liquids, Slurries, Pastes, and Mashes
- Output:
- Powder with 3%–10% moisture content
- Temperature:
- Heat source temperature 50°C to 200°C
- Additional Feature:
- Stirring, Mild Crushing
Liofilizador Piloto
Categorias: Liofilizador, Liofilizador Comercial, Liofilizador de Laboratório
Cutting-Edge Precision Freeze Drying Technology:
The Pilot Freeze Dryer stands out for its accuracy and precision, making it a crucial tool in sectors like pharmaceuticals, biotechnology and food processing. It upholds the chemical and structural integrity of products by drying them at low temperature under vacuum, and offers configurable shelf layouts to accommodate substances ranging from delicate biological materials to sturdy chemical compounds.
- Input:
- Liquids, extracts, blocks, slices, strips
- Output:
- Dehydrated liquids, concentrated extracts, dried blocks, slices and strips
- Temperature:
- Capable of achieving temperatures as low as -55°C
- Additional Feature:
- Defrost System
Liofilizador de Bancada
Categorias: Liofilizador, Liofilizador de Laboratório
Compact Freeze Drying for Lab and Small-Scale Production:
The Benchtop Freeze Dryer brings full freeze-drying capability to a footprint that fits a lab bench or small production room. Automated controls streamline each cycle, while low-temperature vacuum drying preserves the structure and properties of pharmaceutical materials, biological specimens and food products — a dependable choice for drug and vaccine preparation, sample preservation and small-batch trials.
- Input:
- Pharmaceutical materials, biological specimens, food products
- Output:
- Freeze-dried product with preserved structure and properties
- Type:
- Laboratory / small-scale vacuum freeze drying
- Cold Trap:
- Down to -80°C
Liofilizador Redondo
Categorias: Liofilizador, Liofilizador Comercial, Liofilizador Industrial
Maximize Output with Cylindrical-Chamber Freeze Drying:
The Round Freeze Dryer uses a cylindrical chamber that maximizes space usage for large-batch freeze drying at industrial scale. Built to handle big batches without compromising quality or efficiency, it helps companies expand freeze-drying capacity for pharmaceuticals, biological samples and food products while minimizing waste.
- Input:
- Pharmaceuticals, biological samples, food products (large batches)
- Output:
- Freeze-dried product with extended shelf life
- Temperature:
- Adjustable -50°C to -80°C
- Design:
- Cylindrical high-capacity chamber
Liofilizador de Câmara
Categorias: Liofilizador, Liofilizador Industrial
State-of-the-Art Cabinet Freeze Dryer for Industrial Use:
This Cabinet Freeze Dryer is crafted to extract moisture efficiently from a wide array of products. Using a freeze-drying technique, it lowers temperatures to optimal levels and converts moisture directly from solid to vapor — ensuring top-notch preservation and quality without a liquid phase.
- Input:
- Pharmaceutical ingredients, food products, chemical compounds
- Output:
- Stably dried and preserved materials
- Temperature:
- -50°C to -80°C
Equipamentos para Comprimidos, Pós e Processamento Estéril
Secadores a vácuo e de câmara estática processam APIs e intermediários sensíveis ao calor; revestidoras Wurster e granuladores de leito fluidizado formam e revestem grânulos para comprimidos; misturadores sigma e de fita misturam excipientes e princípios ativos; liofilizadores desidratam produtos biológicos e injetáveis, da escala piloto à produção industrial.
Por Que os Fabricantes Farmacêuticos Escolhem Esta Linha
A secagem suave a vácuo e por condução preserva a potência do princípio ativo sem degradação térmica. O revestimento Wurster possibilita formulações com mascaramento de sabor e liberação controlada. Os liofilizadores abrangem desde ensaios de bancada em P&D até a liofilização em lote de produção completa. A construção resistente à corrosão e de fácil limpeza atende aos requisitos de higiene farmacêutica.
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